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Tuesday, 14 November 2017

The probable reasons for leaky blood vessels in severe dengue cases deciphered.

With each passing day the dengue virus is groping individuals at an alarming rate, the recent example being the epidemic situation that aroused in West Bengal, India. In general, the symptoms are fever, headache, vomiting, fatigue, joints pain etc. Till date there is no specific treatment against the virus. The vaccine development for the virus is under process. The only best prevention regimen is the control and eradication of its vector mosquito Aedes agyptii.. 

Severe cases of infection result in the death of the patients wherein the the infected individual develop some life threatening symptoms that include hemorrhagic fever, petechiae (red or purple colored blisters under the skin/) and bleeding nose and gums. Researches are being carried out to rule out the possible biology involved in these conditions so as to develop the drug that can effectively kill the virus. 

One such breakthroughs has been made by scientists at the University of California, Berkeley. They have discovered the plausible case for leaky blood vessels in severe dengue virus infection. They have found that dengue virus NS1

protein is responsible for the disruption of glycocalyx layer lining the blood vessel which leads to the oozing out of the blood vessel components. For full story read here:



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