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Sunday, 16 October 2016

Breast Microbiome: some Prevents while other Causes Cancer

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Its long been known hoe bacteria has been a common dweller on and within us, but bacteria that live in women’s breast tissue have equally important health effect according to a study that published recently in the journal Applied and Environmental Microbiology. The results highlights about the bacteria that are present even in low amounts have dual responsibilities in breast cancer – either increasing risk in some or decreasing risk in others.

Epidemiology suggests that at least one in eight women in US is diagnosed with breast cancer but the origin still remains in vague. Often factors like age, genetic predisposition and some environmental challenges are implicated for the reason of cancer, but now bacteria can also be an added reason under environment factors. Earlier research has provided clues that breast-feeding can lower the risk of cancer and this may be because of breast milk that supports growth of some beneficial microorganisms.

Researchers hunted for bacterial DNA analyzed from breast tissue samples of 58women who were undergoing lumpectomies and mastectomies for either benign or cancerous tumours. They also included 23 healthy participants who were undergoing breast reductions or enhancements. Women who were at a risk of breast cancer have higher levels of Enterobacteriaceae, Bacillus, and Staphylococcus. On the other hand, women who were healthy have other types of bacteria, especially Lactococcus and Streptococcus.

So how these bacteria actually instigate cancer? Enterobacteriaceae and Staphylococcus are involved in DNA damage which is a known route for developing cancer; while other bacteria trigger inflammation. For now researchers are looking forward for animal studies to indentify the exact mechanism.



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