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Wednesday, 13 July 2016

Scientists call for action: Microbes can cause Alzheimer's disease

Senior scientists around the globe came together to provide an editorial which indicates that certain microbes (including a virus and two types of bacteria) are major causative agents for Alzheimer’s disease. The paper was published recently in the journal, Journal of Alzheimer’s disease stressed an urgent need of further research.

This is a major call for action is based on the considerable research published evidences on Alzheimer’s. This editorial has marked his significance with bountiful data suggesting that some microbes can lead to Alzheimers but until now it was dismissed or rather ignored as controversial. For the same reason, proposals for funding for clinical trials have been refused despite the fact that over 400 unsuccessful clinical trials for Alzheimers for over 10years.

“We are saying there is incontrovertible evidence that Alzheimer’s Disease has a dormant microbial component, and that this can be woken up by iron dysregulation. Removing this iron will slow down or prevent cognitive degeneration – we can’t keep ignoring all of the evidence,” Professor Douglas Kell said.

Professor Resia Pretorius of the University of Pretoria, who worked with Douglas Kell on the editorial, said “The microbial presence in blood may also play a fundamental role as causative agent of systemic inflammation, which is a characteristic of Alzheimer’s disease – particularly, the bacterial cell wall component and endotoxin, lipopolysaccharide. Furthermore, there is ample evidence that this can cause neuroinflammation and amyloid-β plaque formation.”



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