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Thursday, 14 July 2016

Chronic fatigue syndrome is associated with altered gut bacteria

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Chronic fatigue syndrome (CFS) is characterized by extreme fatigue which does not heal with rest. In addition there are symptoms like headache, join pains, tender lymph nodes in neck and/or armpits, severe exhaustion and others. It has been long that researchers are searching the cause behind this until the recent research published in the journal Microbiome by group of researchers from Cornell University in Ithaca, NY.

In their research they analyzed stool and blood samples from 48 people who were confirmed with CFS and the results were compared with 39 healthy controls. On comparison, the CFS patients shown lessen bacterial diversity, fewer bacteria with anti-inflammatory response and more pro-inflammatory bacteria. The team notes that such is often seen in patients suffering from Crohn’s disease and Ulcerative colitis.

In blood samples of CFS patients researchers found markers for inflammation. This suggests that bacteria may come in contact with blood due to leaky gut and hence triggered intestinal problems.

Researches in support of this obtained information they could correctly diagnose CFS in 83 percent patients. "In the future, we could see this technique as a complement to other noninvasive diagnoses, but if we have a better idea of what is going on with these gut microbes and patients, maybe clinicians could consider changing diets, using prebiotics such as dietary fibers or probiotics to help treat the disease," explains first author Ludovic Giloteaux, of the Department of Molecular Biology and Genetics at Cornell.

In future, researchers claim that they are still investigating the connection between the altered gut bacteria and the cause of CFS.


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